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Why Alzheimer’s hits women harder than men

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Sex differences in dementia are only just being recognised – but the consequences could change the way we fight the disease.

Diagnosed with Alzheimer’s in 2015, 75-year-old Brenda Whittle still enjoys jigsaws, sewing and dancing. New activities are less appealing, but participating in Alzheimer’s research and drug trials is an exception. She’s so at ease with loud brain scans, she even falls asleep during them.Brenda is one of more than 50 million people worldwide living with dementia – a catch-all category of diseases affecting memory and brain processing, including Alzheimer’s. That number is rising quickly. Globally, experts estimate that 75 million people will live with dementia by 2030 and 131.5 million by 2050.

In Australia, nearly two-thirds of all dementia-related deaths were women; in the US, two-thirds of those living with the disease are women, too. In some cases, dementia even outstrips more famously ‘female’ diseases: US women over 60 are twice as likely to develop Alzheimer’s disease as breast cancer. (Breast cancer remains the leading cause of death for UK women aged 35 to 49).And in England and Wales as well as in Australia, dementia has become the leading cause of death for women, knocking heart disease off the top spot.

“This can’t be sustained by any medical health system – it is too much in terms of numbers, says Antonella Santuccione-Chadha, a physician and Alzheimer’s specialist based in Switzerland. “And as women are more confronted by the disease, we need to investigate the differences between the male and female specifics of it.”

Much of the gender gap comes down to one of dementia’s biggest risk factors: age. The older you are, the more likely you are to develop late-onset Alzheimer’s. Women typically live longer than men, so more have dementia.But recent research hints that we would be wrong to assume that ageing means Alzheimer’s is inevitable. Results from two major Cognitive Function and Ageing Studies (CFAS) suggest that over the last 20 years, new dementia cases in the UK have dropped by 20% – driven mostly by a fall in incidence among men over 65 years old.

Experts say this may be because of public health campaigns targeting heart disease and smoking. Both are risk factors for Alzheimer’s. But because men tend to get heart disease younger and smoke more than women, these campaigns also may have helped stave off these risk factors more for men than women.

Meanwhile, other risk factors for the disease affect women more than men. For example, more women develop depression – and depressed mood has been linked to the onset of Alzheimer’s. Other risk factors affect only women, such as surgical menopause and pregnancy complications like pre-eclampsia, both of which have been linked to cognitive decline in later life.

Social roles, such as caregiving, also may increase the chance of developing dementia. Some research has shown that being a caregiver is, in itself, a risk factor for Alzheimer’s disease, says Annemarie Schumacher, a health psychologist. In the UK, some 60-70% of all unpaid caregivers looking after someone with dementia in particular are women.

“Sex-specific prevention might start from having more of this information about female-specific risk factors,” says Maria Teresa Ferretti, a biomedical researcher in the field of Alzheimer’s disease at the University of Zurich.

This idea is gaining momentum. Advocacy group the Women’s Brain Project (WBP), co-founded by Santuccione-Chadha, Ferretti and Schumacher as well as chemist Gautam Maitra, has just published a major review analysing a decade’s worth of scientific literature on Alzheimer’s, revising existing data and asking scientists to stratify it by sex for the first time.–BBC

“The most obvious differences that come out of the literature are in the display and progression of cognitive and psychiatric symptoms between men and women with Alzheimer’s disease. Based on these new studies we can design new hypotheses and figure out new ways to improve treatment of patients,” says Ferretti.Currently, for example, Alzheimer’s is detected by looking for two toxic proteins that have accumulated in the brain. Evidence suggests no difference in the levels of these proteins, or ‘biomarkers’, in men and women with Alzheimer’s disease. But the women show greater cognitive decline. – BBC



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Camaraderie,reflection and achievements

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Institute of Hospitality Sri Lanka

The 32nd Annual General Meeting (AGM) of the UK-based Institute of Hospitality’s Sri Lanka Chapter was held recently at the Ramada Hotel Colombo,.The event provided an evening of camaraderie , reflection of the past and present achievements,setting new benchmarks for the future

The AGM had the presence of two distinguished guests, the Chief Guest Opposition Leader Sajith Premadasa, and the Guest of Honour British High Commissioner to Sri Lanka, Andrew Patrick. Their inspiring speeches were lauded by all hoteliers who were present at the occasion

A special thanks was extended to Robert Richardson, CEO of the Institute of Hospitality UK, along with his team, sponsors, committee members, and all attendees for making the event memorable.

Dr. Harsha Jayasingh, Past President of the Institute of Hospitality (UK) Sri Lanka Chapter, emphasised the Institute’s longstanding history and the strength of its Sri Lankan branch. “The Institute of Hospitality (IH) UK has a history of 86 years, and we are proud to be the Sri Lanka Branch. IH Sri Lanka is much stronger now with many members from all areas of the hospitality industry,” he stated.

Dr. Jayasingh highlighted the significant role of tourism in Sri Lanka’s economy,. He said tourism it is the third-largest source of revenue for the country. “Tourism accounts for about 13.3% of total foreign exchange earnings and employs 450,000 people directly and indirectly. The hospitality industry in this island of pearl holds tremendous potential for economic growth, job creations, and cultural exchange,” he added.

He also pointed out more women should be attracted to the industry and advocated for the use of technology in hospitality sector to attract the younger generation.

The newly appointed Chairman Ramesh Dassanayake spoke about the challenges faced by the industry, including the reluctance of youth to join the sector. . Dassanayake expressed concerns over the migration of staff between hotels and the overall ‘brain drain’ in the sector. ” We must maintain high standards in the hotel We must try to attract tourists to Sri Lanka, we must have with many facilities Hence, hotel schools and other professional institutions involved in skills development mustincrease their intakes,” he pointed out.

Chief Guest Sajith Premadasa emphasised the importance of eco tourism and said “We need to have an environmental policy related to tourism in place,” . .

The 32nd AGM of the Institute of Hospitality UK, Sri Lanka Chapter, was a testament to the strength and potential of Sri Lanka’s hospitality industry. The insights and commitments shared during the event set a new benchmark for the future.(ZC)

Pix by Thushara Attapathu

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He recognizes human identity beyond boundaries of gender, race, nationality and religion.

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Sri Gurudev was in Sri Lanka on the invitation of the Prime Minister Dinesh Gunewardene

Visit of Sri Gurudev to Sri Lanka

Humanitarian, spiritual leader and Global Ambassador of Peace Gurudev Sri Sri Ravi Shankar (Sri Gurudev) was in Sri Lanka on a three day tour on the invitation of the Prime Minister of Sri Lanka Dinesh Gunewardene. Gurudev who inspired a wave of volunteerism and service to moot one of the largest volunteer-based organisations in the world – The Art of Living – visited the various projects under the aegis of the foundation and launched twelve vocational and technical centers around the island. He was accompanied by thousands of followers from Sri Lanka and around the world.

Gurudev who visited Sri Lanka for the sixth time also had a first day cover launched in honour of his visit. He is a strong proponent of spreading happiness, using the unique Sudarshan Kriya, yoga, meditation and practical wisdom to unite people, empower individuals and transform communities. His programmes provide techniques and tools to live a deeper, more joyous life, while his non-profit organisations recognize the human identity beyond the boundaries of gender, race, nationality and religion.

The Art of Living which has more than 30,000 teachers and over one million volunteers across 180 countries has touched in excess of five hundred million people around the world. CNN called it “Life Changing” and The Washington Post headlined it, “Fresh air to millions”.

In Trincomalee, Gurudev met with war victims and had a heartwarming engagement with the children from the children’s homes run by the Foundation. He also visited the Koneswara Temple in Trincomalee and graced the Kumbhabhishekam at Seetha ecogPnize the human identity beyond the boundaries of gender, race, nationality and religion. Amman temple at Nuwara Eliya. He held discussions with the trustees on the progress of the foundation’s social service projects, while also holding a special event – Ekamuthuwa – attended by a large number of dignitaries and his devotees from around the world.

His time with the Prime Minister was spent discussing the prospects of unity in diversity and uniting Sri Lanka by adding happiness into the formula of living. In addition he had discussions with the Speaker of the Parliament of Sri Lanka Mahinda Yapa Abeywardena, prominent business stewards and civil society leaders.

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Bridal shows with opulence and luxury at The Epitome hotel in Kurunegala

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by Zanita Careem

Envison your dream wedding day come to life at the Epitome Hotel, a prestigious city hotel in Kurunegala offering an unrivalled luxury rendors experience for weddings.

The venue is designed to embody opulence and luxury from all quarters for a spectacular wedding in kurunegala,Thier ballroom is the largest banquet facility in Sri Lanka It can be divided into six luxurious pillarless wedding halls on the ground floor and 25pax smaller banquet halls.

It can be easily named as a five star heaven in the heart of the city contributing to a myriad of immense experiences tailored to inspire and delight wedding experiences.

From opulent décor set up to exquisite table decor, lavish food, every detail is meticulously curated to spark your imagination and ignite creativity for a perfect wedding. The previous prestigious wedding shows season one and season two attracted large crowds

were unique events which gave the wedding vendors and potential clients had an opportunity to connect and interact with each other. Beyond being a showcase it was a chance for the wedding vendors to unite and contribute to the vibrancy of the wedding industry. The wedding show covered all area of the bridal industry providing a comprehensive variety of bridal supplies from Sri lanka and became the most popular bridal exhibitions in Kurunegala.This bridal exhibitions allowed brides and grooms to experience first hand the products and services available from suppliers in Sri Lanka

These wedding shows held at The Epitome created a benchmark and gave an opportunity for vendors to create connections to the utmost satisfaction said Harshan Lakshita Executive Director. of the magnificent Hotel

Our wedding shows featured experts and professionals in every field‘ It covered all areas of the bridal industry provided a comprehensive variety of bridal supplies from Sri lanka and became most popular bridal exhibition in this region.We are always open to everyone to join us at our wedding shows in the future. It is an opportunity to discover the incredible talent within our local wedding and bridal vendors to make meaningful relationships and plan thier special day at our breathtaking hotel The Epitome said General Manager Kavinda Caldera

The Epitome Hotel’s bridal show which will be held end of June will buzz with great ideas,advice and inspiration for all those who plan thier dream wedding

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The Hotel Epitome’s Wedding Season 3 will marked excellence, celebration and inspiration for those in the wedding industry. The exhibition halls will resonate with ideas on exquisite bridal wear to decor, florists , photography etc and showshowcase the rich tapestry of talent within the local wedding industry. .

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